Artemisia Annua: An antibiotic alternative in the poultry industry

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Authors

  • Hafiz Muhammad Nouman Kirikkale University
  • Roshan Riaz
  • Ibrar Ahmed
  • Gökhan Şen

Keywords:

Antibiotics alternative, antibiotics resistance, Artemisia annua, poultry ındustry

Abstract

The poultry industry is based on raising fast-growing chickens. In recent decades, several antibiotics have been employed as growth promoters in the chicken industry, but antibiotic use is banned in the poultry industry due to increased antibiotic resistance and negative impacts on human health. Scientists started searching for alternative antibiotic products as antibiotic resistance increased. Probiotics, prebiotics, organic acids, plant extracts, etheric oils, and immunological stimulants are some of the alternatives. In recent years, these products have improved animal performance, increased animal productivity, prevented and controlled enteric infections, and reduced antibiotic use in animal agriculture. Artemisia, which is currently in scattered form in various research papers, and to draw the attention of experts throughout the world to the Artemisia species' untapped potential. Artemisia annua is also known as sweet wormwood, sweet Annie, and sweet annual wormwood (Chinese: qngho). It's a common wormwood species native to Asia's temperate zones. The active ingredient present in the Artemisia genus is Artemisinin, and chemically it contains both volatile and non-volatile constituents. Biological activities of the Artemisia genus include antibacterial, anti-inflammatory, anti-malarial, anti-coccidial, anti-oxidant, and anti-tumor effects. It has positive effects on growth performance, FCR, gut health, immunity, digestibility, and meat quality of broilers. In conclusion, Artemisia annua is the best alternative product for avoiding anti-microbial resistance in the poultry industry without compromising growth and production. This study aims to review the research conducted on the Artemisia genus.

References

Agyare C, Boamah VE, Zumbi CN, Osei FB. 2018. Antibiotic use in poultry production and its effects on bacterial resistance. Antimicrob Resist-A Global Threat, 33-50.

Ajah P, Eteng MJ. 2010. Phytochemical screening and histopathological effects of single acute dose administration of Artemisia annua L. on testes and ovaries of Wistar rats. African Journal of Biochemistry Research, 4(7), 179-185.

Akyildiz S, Denli M. 2016. Application of plant extracts as feed additives in poultry nutrition. Animal Science, 59, 2285-5750.

Alanis AJ. 2005. Resistance to antibiotics: are we in the post-antibiotic era? Archives of Medical Research, 36(6), 697-705.

Allen PC, Lydon J, Danforth HD. 1997. Effects of components of Artemisia annua on coccidia infections in chickens. Poultry Science, 76(8), 1156-1163.

Archile-Contreras A, Purslow PP. 2011. Oxidative stress may affect meat quality by interfering with collagen turnover by muscle fibroblasts. Food Research International, 44(2), 582-588.

Attia YA, Hamed RS, Bovera F, Al-Harthi MA, El-Hamid A, Esposito L, Shahba HA. 2019. Milk thistle seeds and rosemary leaves as rabbit growth promoters. Animal Science Papers and Reports, 37(3), 277-295.

Azad M, Kikusato M, Maekawa T, Shirakawa H, Toyomizu MJ, Molecular PPA. 2010. Metabolic characteristics and oxidative damage to skeletal muscle in broiler chickens exposed to chronic heat stress. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology,155(3), 401-406.

Baghban-Kanani P, Hosseintabar-Ghasemabad B, Azimi-Youvalari S, Seidavi A, Ragni M, Laudadio V, Tufarelli VJ. 2019. Effects of using Artemisia annua leaves, probiotic blend, and organic acids on performance, egg quality, blood biochemistry, and antioxidant status of laying hens. The Journal of Poultry Science, 56(2), 120-127.

Belhadj Slimen I, Najar T, Ghram A, Dabbebi H, Ben Mrad M, Abdrabbah MJ. 2014. Reactive oxygen species, heat stress and oxidative-induced mitochondrial damage. A review. International journal of hyperthermia, 30(7), 513-523.

Bhakuni R, Jain D, Sharma R, Kumar SJ. 2001. Secondary metabolites of Artemisia annua and their biological activity. Current Issue,35-48.

Brisibe EA, Umoren UE, Owai PU, Brisibe F. 2008. Dietary inclusion of dried Artemisia annua leaves for management of coccidiosis and growth enhancement in chickens. African Journal of Biotechnology, 7(22).

Castanon J. 2007. History of the use of antibiotic as growth promoters in European poultry feeds. Poultry Science, 86(11), 2466-2471.

Cavani C, Petracci M, Trocino A, Xiccato, G. 2009. Advances in research on poultry and rabbit meat quality. Italian Journal of Animal Science, 8(2), 741-750.

Cherian G, Orr A, Burke I, Pan WJ2013. Feeding Artemisia annua alters digesta pH and muscle lipid oxidation products in broiler chickens. Poultry Science,92(4), 1085-1090.

Choct M. 2001. Alternatives to in-feed antibiotics in monogastric animal industry. ASA Technical Bulletin. AN30, 1-6.

Cogliani C, Goossens H, Greko C. 2011. Restricting anti-microbial use in food animals: lessons from Europe. Microbe, 6(6), 274.

Daikos GL, Koutsolioutsou A, Tsiodras S, Theodoridou M, Koutouzis EI, Charissiadou A, Pangalis A, Michos AG, Chaidopoulou F, Braoudaki M. 2008. Evolution of macrolide resistance in Streptococcus pneumoniae clinical isolates in the prevaccine era. Diagnostic Microbiology and Infectious Disease, 60(4), 393-398.

Del Cacho E, Gallego M, Francesch M, Quílez J, Sánchez-Acedo CJP. 2010. Effect of artemisinin on oocyst wall formation and sporulation during Eimeria tenella infection. Parasitology International,59(4), 506-511.

Denli M, Okan F, Uluocak AJ. 2004. Effect of dietary supplementation of herb essential oils on the growth performance, carcass and intestinal characteristics of quail (Coturnix coturnix japonica). South African Journal of Animal Science, 34(3).

Dibner J, Richards J. 2005. Antibiotic growth promoters in agriculture: history and mode of action. Poultry Science, 84(4), 634-643.

Drăgan L, Györke A, Ferreira JF. Pop I, Dunca I, Drăgan M, Mircean V, Dan I, Cozma V. 2014. Effects of Artemisia annua and Foeniculum vulgare on chickens highly infected with Eimeria tenella (Phylum Apicomplexa). Acta Veterinaria Scandinavica, 56(1), 22.

Elwinger K. a, Schneitz C, Berndtson E, Fossum O, Teglöf B, Engstöm B. 1992. Factors affecting the incidence of necrotic enteritis, caecal carriage of Clostridium perfringens and bird performance in broiler chicks. Acta Veterinaria Scandinavica, 33(4), 369-378.

Engberg R M, Grevsen K, Ivarsen E, Fretté X, Christensen LP, Højberg O, Jensen BB, Canibe NJ. (2012). The effect of Artemisia annua on broiler performance, on intestinal microbiota and on the course of a Clostridium perfringens infection applying a necrotic enteritis disease model. Avian Pathology, 41(4), 369-376.

Ferreira JdS, Janick J. 1994. Production and detection of artemisinin from Artemisia annua. Internat. Symposium on Medicinal and Aromatic Plants 390,

Gholamrezaie SL, Mohammadi M, Jalali, SJ, Abolghasemi S, Roostaei AM. 2013. Extract and leaf powder effect of Artemisia annua on performance, cellular and humoral immunity in broilers. Iranian Journal of Veterinary Research, 1(42), 15-20.

Grasman KA. 2010. In vivo functional tests for assessing immunotoxicity in birds. In Immunotoxicity Testing. Springer, 387-398.

Guo S, Ma J, Xing Y, Xu Y, Jin X, Yan S, Shi B. 2020. Artemisia annua L. aqueous extract as an alternative to antibiotics improving growth performance and antioxidant function in broilers. Italian Journal of Animal Science, 19(1), 399-409.

Györke A, Pop L, Cozma VJP. 2013. Prevalence and distribution of Eimeria species in broiler chicken farms of different capacities. Parasite, 20, 50.

Hafez H. 2005. Governmental regulations and concept behind eradication and control of some important poultry diseases. World's Poultry Science Journal, 61(4), 569-582.

Heywood V, Humphries CJB, Compositae Cot. 1977. Anthemideae systematic review. Biology and Chemistry of the Compositae.

Hofacre C, Froyman R, Gautrias B, George B, Goodwin M, Brown J. 1998. Use of Aviguard and other intestinal bioproducts in experimental Clostridium perfringens-associated necrotizing enteritis in broiler chickens. Avian Diseases, 579-584.

Hoste H, Jackson F, Athanasiadou S, Thamsborg SM, Hoskin SO. 2006. The effects of tannin-rich plants on parasitic nematodes in ruminants. Trends Parasitol, 22(6), 253-261.

Hsieh PC, Mau JL, Huang SH.2001. Anti-microbial effect of various combinations of plant extracts. Food Microbiology, 18(1), 35-43.

Iqbal S, Younas U, Chan KW, Zia-Ul-Haq M, Ismail MJM. 2012. Chemical composition of Artemisia annua L. leaves and antioxidant potential of extracts as a function of extraction solvents. Molecules, 17(5), 6020-6032.

Iranshahi M, Emami SA, Mahmoud SM. 2007. Detection of sesquiterpene lactones in ten Artemisia species population of Khorasan provinces. Iranian Journal of Basic Medical Sciences, 3(35), 183-188.

Jin SH, Corless A, Sell JJW. 1998. Digestive system development in post-hatch poultry. World Poultry Science Journal, 54(4), 335-345.

Jones F, Ricke S. 2003. Observations on the history of the development of anti-microbials and their use in poultry feeds. Poultry Science, 82(4), 613-617.

Lara LJ, Rostagno MHJA. 2013. Impact of heat stress on poultry production. Animals, 3(2), 356-369.

Malik AA, Ahmad J, Mir SR, Ali M, Abdin MJI. 2009. Influence of chemical and biological treatments on volatile oil composition of Artemisia annua Linn. Industrial Crops and Products, 30(3), 380-383.

Maron DF, Smith TJ, Nachman KE. 2013. Restrictions on anti-microbial use in food animal production: an international regulatory and economic survey. Globalization and Health, 9(1), 1-11.

Monnet DL. 2005. Antibiotic development and the changing role of the pharmaceutical industry. International Journal of Risk and Safety in Medicine, 17(3, 4), 133-145.

Mulder R. 2011. Current EU regulations for the production and processing of (safe) poultry meat. In: Published 10/20/2011 http://en.engormix.com/MA-poultry-industry/health.

Neu HC. 1992. The crisis in antibiotic resistance. Science. 257:1064–1073.

Niu Z, Liu F, Yan Q, Li WJP. 2009. Effects of different levels of vitamin E on growth performance and immune responses of broilers under heat stress. Poultry Science, 88(10), 2101-2107.

Nofal SM, Mahmoud SS, Ramadan A, Soliman G, Fawzy RJ, Sciences M. (2009). Anti-diabetic effect of Artemisia judaica extracts. Research Journal of Medicine and Medical Sciences,4(1), 42-48.

Nollen EA, Morimoto RIJJ. 2002. Chaperoning signaling pathways: molecular chaperones as stress-sensingheat shock'proteins. Journal of Cell Science, 115(14), 2809-2816.

Ogle M. 2013. In meat we trust: An unexpected history of carnivore America. Houghton Mifflin Harcourt.

Organization WH. 2006.WHO monograph on good agricultural and collection practices (GACP)‎ for Artemisia annua L. World Health Organization.

Patočka J, Plucar BJJ. 2003. Pharmacology and toxicology of absinthe. Journal of Applied Biomedicine, 1(4), 199-205.

Pradeep C, Kuttan G. 2004. Piperine is a potent inhibitor of nuclear factor-κB (NF-κB), c-Fos, CREB, ATF-2 and proinflammatory cytokine gene expression in B16F-10 melanoma cells. International Immunopharmacology, 4(14), 1795-1803.

Rahimi S, Teymori-Zadeh Z, Torshizi K, Omidbaigi R, Rokni H. 2011. Effect of the three herbal extracts on growth performance, immune system, blood factors and intestinal selected bacterial population in broiler chickens. Journal of Agricultural Science and Technology, 13(4), 527-539.

Rice LB. 2009. The clinical consequences of anti-microbial resistance. Current Opinion in Microbiology, 12(5), 476-481.

Ryu JC, Park SM, Hwangbo M, Byun SH, Ku SK, Kim YW, Kim SC, Jee SY, Cho IJJ. 2013. Methanol extract of Artemisia apiacea hance attenuates the expression of inflammatory mediators via NF-κB inactivation. Evidence-Based Complementary and Alternative Medicine, 494681.

Settar P, Yalcin S, Turkmut L, Ozkan S, Cahanar AJP. 1999. Season by genotype interaction related to broiler growth rate and heat tolerance. Poultry Science, 78(10), 1353-1358.

Simonnet X, Quennoz M, Carlen C. 2006. New Artemisia annua hybrids with high artemisinin content. XXVII International Horticultural Congress-IHC2006: International Symposium on Asian Plants with Unique Horticultural 769,

Singer RS, Hofacre CLJ. 2006. Potential impacts of antibiotic use in poultry production. Avian Diseases,50(2), 161-172.

Song Z, Cheng K, Zheng X, Ahmad H, Zhang L, Wang TJP. 2018. Effects of dietary supplementation with enzymatically treated Artemisia annua on growth performance, intestinal morphology, digestive enzyme activities, immunity, and antioxidant capacity of heat-stressed broilers. Poultry Science, 97(2), 430-437.

Stutz M, Lawton G. 1984. Effects of diet and anti-microbials on growth, feed efficiency, intestinal Clostridium perfringens, and ileal weight of broiler chicks. Poultry Science, 63(10), 2036-2042.

Sadiq A, Hayat MQ, Ashraf M. 2014. Ethnopharmacology of Artemisia annua L.: A review. Artemisia annua-Pharmacology and Biotechnology, 9-25.

Taheri H, Rahmani H, Pourreza JJI. 2005. Humoral immunity of broilers is affected by oil extracted propolis (OEP) in the diet. International Journal of Poultry Science,4(6), 414-417.

Tajodini M, Saeedi H, Moghbeli P. 2015. Use of black pepper, cinnamon and turmeric as feed additives in the poultry industry. World's Poultry Science Journal, 71(1), 175-183.

Turner K, Ferreira J. 2005. Potential use of Artemisia annua in meat goat production systems. Proceedings of American Forage and Grassland Council Symposium, 14, 221-225.

Willcox M, Bodeker G, Bourdy G, Dhingra V, Falquet J, Ferreira JF, Graz B, Hirt HM, Hsu E, de Magalhães PM. 2004. Artemisia annua as a traditional herbal antimalarial. Traditional Medicinal Plants and Malaria, 4, 43-59.

Williams RJA. 1995. Epidemiological studies of coccidiosis in the domesticated fowl (Gallus gallus): I. The fate of ingested oocysts of Eimeria tenella during the prepatent period in susceptible chicks. Applied Microbiology,36(2), 83-89.

Wan XL, Song ZH, Niu Y, Cheng K, Zhang JF, Ahmad H, Zhang LL and Wang T. 2017. Evaluation of enzymatically treated Artemisia annua L. on growth performance, meat quality, and oxidative stability of breast and thigh muscles in broilers. Poulty Science 96, 844–850.

Zhang Z, Jia G, Zuo J, Zhang Y, Lei J, Ren L, Feng DJP. 2012. Effects of constant and cyclic heat stress on muscle metabolism and meat quality of broiler breast fillet and thigh meat. Poultry Science, 91(11), 2931-2937.

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Published

2022-12-20

How to Cite

Nouman, H. M. ., Riaz, R., Ahmed, I., & Şen, G. (2022). Artemisia Annua: An antibiotic alternative in the poultry industry. International Journal of Veterinary and Animal Research (IJVAR), 5(3), 174–180. Retrieved from https://ijvar.org/index.php/ijvar/article/view/550

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Review Article