A New Era Under Soil Based Probiotics for Anti-Pruritic Combat Among Cats with Feline Atopic Skin Syndrome

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Authors

  • Kerem Ural
  • Hasan Erdogan
  • Songul Erdogan

Keywords:

Atopic skin syndrome, feline, soil-based probiotic

Abstract

Present research was conducted at the University of Aydin Adnan Menderes, Faculty of Veterinary. In a total of 10 cats with pruritic dermatoses were allocated, classified [Feline atopic skin syndrome (FaSs)] and adapted to the retrospective case controlled study on the basis of Polycheck in vitro Allergy Test, clinical signs, dermatoscopic and cytological examination. No prior drug prescription, nor immunosuppressive treatment were evident, which was an inclusion criteria. Complete blood count, serum biochemistry, and endocrine panels were all deemed available on days 0 and 21 for all cats involved. The Feline Dermatitis Extent and Severity Index (FeDESI) and a 10 cm visual analog scale (VAS) were deemed available as relevant prognostic parameters. A three strain invoving soil-based probiotic used via rectal route significantly decreased FEDESI and VAS pruritus scores after 10 days of rectal use. Pre-treament day 0 FEDESI scores (median ± SD) (106.3 ± 41.38), were significantly higher than scores on day 10 (15.3 ± 10.53) switching the severity of the disease to mild status in all cases. Furthermore, day 0 VAS pruritus scores were 7.4 ± 1.78 (mean ± SD) (prior to treatment), whereas owner VAS pruritus score was decreased to 1.3 ± 1.06 (mean ± SD) significantly (p=0.005). It should not be unwise to draw preliminary conclusion that 3 chained soil-based Bacillus probiotic was capable of short term cure for FaSs. Bacillus probiotics with safety usage should be added to therapeutical armamentarium of FaSs.

References

Benson KF, Redman KA, Carter SG, Keller D, Farmer S, Endres JR, Jensen GS. 2012 Probiotic metabolites from Bacillus coagulans GanedenBC30TM support maturation of antigen-presenting cells in vitro. World journal of gastroenterology, 18(16): 1875.

Bowe WP, Logan AC. 2010. Clinical implications of lipid peroxidation in acne vulgaris: old wine in new bottles. Lipids in health and disease, 9(1): 1-11.

Ciacci C, Cavallaro R, Iovino P, Sabbatini F, Palumbo A, Amoruso D, Mazzacca G. 2004. Allergy prevalence in adult celiac disease. Journal of allergy and clinical immunology, 113(6): 1199–1203.

Coppola MDM, Gil-Turnes C. 2004. Probiotics and immune response. Ciência rural, 34: 1297–12303.

Danilova I, Sharipova M. 2020. The practical potential of Bacilli and their enzymes for industrial production. Frontiers in microbiology, 11: 1782.

Diesel A, DeBoer DJ. 2011. Serum allergen-specific immunoglobulin E in atopic and healthy cats: comparison of a rapid screening immunoassay and complete-panel analysis. Veterinary dermatology. 22(1): 39– 45.

Fasano A. 2011. Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer. Physiological reviews, 91: 151–175.

Fasano A, Catassi C. 2012. Celiac disease. The new england journal of medicine, 367(25): 2419-2426.

Favrot C, Rostaher A, Fischer N. 2014. Clinical symptoms, diagnosis and therapy of feline allergic dermatitis. Schweizer archive für tierheilkunde, 156: 327– 335.

Feliciano MAR, Saad FMOB, Logato PVR, Aquino AA, José VA, Roque NC. 2009. Effects of probiotics on digestibility, faecal score, and haematologic characteristics in dogs. Arquivo Brasileiro de medicine veterinaria e zootecnia, 61: 1268–1274.

Félix AP, Netto MVT, Murakami FY, Brito CBMD, Oliveira SGD, Maiorka A. 2010. Digestibility and faecal characteristics of dogs fed with Bacillus subtilis in diet. Ciência rural, 40: 2169–2173.

Guo S, Al‐Sadi R, Siad HM, Ma TY. 2013. Lipopolysaccharide causes an increase in intestinal tight junction permeability in vitro and in vivo by inducing enterocyte membrane expression and localization of TLR‐4 and CD14. American Journal of Pathology, 182(2): 375–387.

Halliwell R, Banovic F, Mueller RS, Olivry T. 2021. Immunopathogenesis of the feline atopic syndrome. Veterinary dermatology, 32(1): 13– 25.

Halliwell R, Pucheu‐Haston CM, Olivry T, Prost C, Jackson H, Banovic F, Mueller RS. 2021a. Feline allergic diseases: introduction and proposed nomenclature. Veterinary dermatology, 32(1): 8.

Hill PB, Lau P, Rybnicek J. 2007. Development of an owner‐assessed scale to measure the severity of pruritus in dogs. Veterinary dermatology, 18(5): 301-308.

Hoa NT, Baccigalupi L, Huxham A, Smertenko A, Van PH, Ammendola S, Cutting SM. 2000. Caracterização de espécies de Bacillus utilizadas para bacterioterapia oral e bacterioprofilaxia de desordens gastrointestinalis. Journal of applied environmental microbiology, 66: 5241–5247.

Jensen GS, Benson KF, Carter SG, Endres JR. 2010. GanedenBC30™ cell wall and metabolites: anti-inflammatory and immune modulating effects in vitro. BMC Immunology, 11(1): 1-14.

Jones SE, Knight KL. 2012. Bacillus subtilis-mediated protection from Citrobacter rodentium-associated enteric disease requires espH and functional flagella. Infection and immunity, 80(2): 710–719.

Jones SE, Paynich ML, Kearns DB, Knight KL. 2014. Protection from intestinal inflammation by bacterial exopolysaccharides. The journal of immunology, 192(10): 4813–4820.

Kell DP, Pretorius E. 2015. On the translocation of bacteria and their lipopolysaccharides between blood and periperhal locations in chronic inflammatory diseases: the central roles of LPS and LPS‐induced cell death. Integrative biology, 7(11): 1339-1377.

Kerr KR, Cutler S, Burke M, Swanson KS. 2011. Evaluation of Bacillus subtilis PTA 6737 in domestic cats. The federation of American societies for experimental biology journal, 25: 217-7.

Majamaa H, Isolauri E. 1996. Evaluation of the gut mucosal barrier: evidence for increased antigen transfer in children with atopic eczema. Journal of allergy and clinical immunology, 97: 985–990.

Marsella R Olivry T, Carlotti DN. 2011. International task force on canine atopic dermatitis: Current evidence of skin barrier dysfunction in human and canine atopic dermatitis. Veterinary dermatology, 22: 239–248.

Moir A. 2006. How do spores germinate? Journal of applied microbiology, 101: 526–530.

Mueller RS, Nuttall T, Prost C, Schulz B Bizikova, P. 2021. Treatment of the feline atopic syndrome – a systematic review. Veterinary dermatology, 32: 43-48.

Nimmo Wilkie JS, Yager J, Wilkie BN. 1991. Abnormal cutaneous response to mitogens and a contact allergen in dogs with atopic dermatitis. Veterinary immunology and immunopathology, 28: 97–106.

Nuttall TJ, Steen RV, Cawood MI, Houghton CA. 2004. FC-49 feline dermatitis extent and severity index: A pilot study. Veterinary dermatology, 15: 36-36.

Ojetti V, De Simone C, Aguilar Sanchez J, Capizzi R, Migneco A, Guerriero C, Gasbarrini A. 2006. Malabsorption in psoriatic patients: cause or consequence? Scandinavian journal of gastroenterology, 41(11): 1267-1271.

O’Neill CA, Monteleone G, McLaughlin JT, Paus R. 2016. The gut-skin axis in health and disease: A paradigm with therapeutic implications. Bioessays, 38(11): 1167–1176.

Paap PM, Laak VDL, Smit JI, Nakamura N, Beynen AC. 2016. Administration of Bacillus subtilis C-3102 (Calsporin®) may improve faeces consistency in dogs with chronic diarrhea. Research opinions in animal and veterinary science, 6: 256–260.

Paik W, Alonzo F, Knight KL. 2019. Probiotic Exopolysaccharide Protects against Systemic Staphylococcus aureus Infection, Inducing Dual-Functioning Macrophages That Restrict Bacterial Growth and Limit Inflammation. Infection and immunity, 87: 791-818.

Paynich ML, Jones-Burrage SE, Knight KL. 2017. Exopolysaccharide from Bacillus subtilis Induces Anti-Inflammatory M2 Macrophages That Prevent T Cell-Mediated Disease. The journal of immunology, 198: 2689–2698.

Ravens PA, Xu BJ, Vogelnest LJ. 2014. Feline atopic dermatitis: a retrospective study of 45 cases (2001–2012). Veterinary dermatology, 25(2), 95- e28.

Saarialho‐Kere U. 2004. The gut skin axis. J Pediatr Gastroenterol Nutr. 39(3): 734–735.

Santoro D, Pucheu‐Haston CM, Prost C, Mueller RS, Jackson H. 2021. Clinical signs and diagnosis of feline atopic syndrome: detailed guidelines for a correct diagnosis. Veterinary dermatology, 32(1): 26-e6.

Schmidt V, Buckley LM, Mcewan NA, Rème CA, Nuttall TJ. 2012. Efficacy of a 0.0584% hydrocortisone aceponate spray in presumed feline allergic dermatitis: An open label pilot study. Veterinary dermatology, 23: 11-16.

Stokes JH, Pillsbury DM. 1930. The Effect on the Skin of emotional and nervous states: iii. Theoretical and practical consideration of a gastro-intestinal mechanism. Archives of dermatology and syphilology, 22(6): 962–993.

Swartzendruber JA, Incrocci RW, Wolf SA, Jung A, Knight KL. 2019. Bacillus subtilis exopolysaccharide prevents allergic eosinophilia. Allergy, 74(4): 819.

Tam NK, Uyen NQ, Hong HA, Duc LH, Hoa TT, Serra CR, Cutting SM. 2006. O ciclo de vida intestinal de Bacillus subtilis e parentes próximos. Journal of bacteriology, 188: 2692–2700.

Tunsagool P, Ploypetch S, Jaresitthikunchai J, Roytrakul S, Choowongkomon K, Rattanasrisomporn J. 2021. Efficacy of cyclic lipopeptides obtained from Bacillus subtilis to inhibit the growth of Microsporum canis isolated from cats. Heliyon, 7(9): e07980.

Varionen E, Vainio E, Kalimo K. 2000. Antigliadin IgE‐indicator of wheat allergy in atopic dermatitis. Allergy, 55: 386–391.

Zamora-Pineda J, Kalinina O, Osborne BA, Knight KL. 2022. Probiotic Molecules That Inhibit Inflammatory Diseases. Applied sciences, 12(3): 1147.s

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Published

2022-08-27

How to Cite

Ural, K., Erdogan, H., & Erdogan, S. (2022). A New Era Under Soil Based Probiotics for Anti-Pruritic Combat Among Cats with Feline Atopic Skin Syndrome. International Journal of Veterinary and Animal Research (IJVAR), 5(2), 89–93. Retrieved from https://ijvar.org/index.php/ijvar/article/view/546

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Research Articles

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