The Comparison of The Effects of Medetomidine and Alfaxalone on Sedation in Cats

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  • Mert Soykan Besler
  • Zeynep Pekcan


Alfaxalone, anesthesia, cat, medetomidine, sedation


This study was conducted to compare the sedative and cardiovascular effects of alfaxalone and medetomidine in cats. In the study, 18 owned cats brought for X-ray, ultrasound, dental examination, ear diseases examination, and bandage change were used. The cats were randomly divided into two groups; 4 mg/kg alfaxalone was intravenously administered to one group and 0.08 mg/kg medetomidine to the other group. After the application, movement changes and sedation conditions were recorded. Sedation score, analgesia score, heart rate, respiratory rate, and side effects were also recorded. The sedation score was higher and the duration of sedation was longer in the medetomidine group, and the differences were statistically significant. As a result, it was concluded that alfaxalone and medetomidine have clinically similar sedative and analgesic efficacy, medetomidine should be preferred in applications requiring prolonged sedation in cats, and alfaxalone is more reliable in animals with cardiovascular problems.




How to Cite

Besler, M. S., & Pekcan, Z. (2021). The Comparison of The Effects of Medetomidine and Alfaxalone on Sedation in Cats. International Journal of Veterinary and Animal Research (IJVAR), 4(2), 44–48. Retrieved from



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