Efficacy of Amoxicillin-Clavulanic Acid, Ceftiofur Sodium and Florphenicol in Purebred Arabian Mares Susceptible to Post-Breeding Endometritis
Post-breeding endometritis is among the most important causes of infertility in purebred Arabian mares. In this study, it was aimed to evaluate the diagnosis of post-breeding endometritis by various intrauterine antibiotics administrations and to determine the most successful treatment protocol in terms of achieving pregnancy. For this purpose, a total of 80 purebred Arabian mares, that had no reproductive problems in the previous season but were susceptible to post-breeding endometritis in the season of the study were included. During the ovulation follow up performed 24 and 48 hours after the insemination, mares with an intrauterine fluid accumulation larger than 2 cm in diameter were considered susceptible to post-breeding endometritis. These mares were divided into 3 different intrauterine treatment groups: Group I (Amoxicillin-Clavulanic Acid, n=20), Group II (Ceftiofur Sodium, n=20) and Group III (Florfenicol, n=20). The mares in the control group were not given any treatment other than placebo (0.09% NaCl) (Group IV, n=20). Oxytocin (IM) was administered to all mares in the treatment and control groups 2-3 hours after the application, in 3 doses at 6 hour intervals. An examination was performed at the 24th and 48th hours following the ovulation to determine ovulation. Pregnancy examinations were carried out by ultrasound on the 15th, 30th and 45th days after the ovulation. As a result of the treatments, pregnancy rates among the groups were found as 40%, 60%, 55% and 20%, respectively. As a result, it was concluded that Ceftiofur sodium and Florfenicol applications are effective (p<0.05) in terms of pregnancy rates in mares susceptible to post-breeding endometritis.
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