Unraveling Microbiome: The Role of Microbiota in Patients’ Response to Oncological Treatment and Its Influence on Host-biochemistry

  • Elisha Apatewen Akanbong Kirikkale University
  • Ali Şenol
  • Mert Sudağıdan
  • Alparslan Kadir Devrim
Keywords: Biochemical parameters, cancer chemotherapy, commensal microbes, microbiome, microbiota

Abstract

Despite the implication of viruses and bacteria in oncogenesis, commensal microbes play a beneficial role in anticancer therapy. Microbiota regulates responses made to various types of cancer chemotherapy by affecting the mechanism of action and toxicity of these therapies. From birth, microbiota confers innate and acquired immune responses and its role in modulating health and diseases has recently been appreciated. Increasing evidence also suggests that microbiota affects the pattern of body energy balance thus; they have a correlation with obesity, obesity-related complications and insulin resistance. Hence, microbiota has attracted the interest of researchers. However, there is little, if any, robust evidence-based review on their role in patients’ response to cancer therapy and their influence on host-biochemistry thus, this review aimed to achieve that.

Published
2021-09-16
How to Cite
Akanbong, E., Şenol, A., Sudağıdan, M., & Devrim, A. (2021). Unraveling Microbiome: The Role of Microbiota in Patients’ Response to Oncological Treatment and Its Influence on Host-biochemistry. International Journal of Veterinary and Animal Research (IJVAR), 4(2), 69-77. Retrieved from http://ijvar.org/index.php/ijvar/article/view/489
Section
Review Article